Coagulation Disorders USMLE Step 1 Practice Question
A 35-year-old woman with a history of three miscarriages presents with a deep vein thrombosis in the right lower extremity. Physical examination reveals livedo reticularis on her legs. Laboratory studies show a prolonged aPTT that does not correct with a 1:1 mixing study. Which of the following is the most likely diagnosis?
Answer choices
- AAntiphospholipid syndromeCorrect answer
- BFactor V Leiden mutation
- CProtein C deficiency
- DProthrombin G20210A mutation
- EDisseminated intravascular coagulation
- FSystemic lupus erythematosus without antiphospholipid antibodies
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