Coagulation Disorders USMLE Step 1 Practice Question
A 32-year-old woman with no past medical history presents with severe abdominal pain, watery diarrhea, and confusion. Vital signs show BP 158/94 mmHg, HR 102/min, RR 20/min, Temp 38.2°C. Laboratory findings reveal thrombocytopenia (22,000/μL), schistocytes on peripheral blood smear, creatinine 2.8 mg/dL, and normal PT/PTT. She denies recent antibiotic use. Which of the following is the most likely diagnosis?
Answer choices
- ADisseminated intravascular coagulation
- BThrombotic thrombocytopenic purpuraCorrect answer
- CSystemic lupus erythematosus
- DHemolytic uremic syndrome
- EImmune thrombocytopenia
- FSepsis-induced thrombocytopenia with acute kidney injury
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