Toxicology USMLE Step 1 Practice Question
A 33-year-old industrial worker presents with severe hand pain and erythema after a hydrofluoric acid spill. Vital signs show HR 110/min, BP 138/88 mmHg, RR 20/min. Serum calcium is 6.2 mg/dL (normal 8.5-10.5). He develops muscle cramps and diffuse ST-segment elevation on ECG. Physical examination reveals no respiratory distress. He has not taken calcium supplements. Which treatment is most appropriate for managing both local and systemic toxicity?
Answer choices
- AProtamine sulfate
- BPyridoxine
- CTopical or intravenous calcium gluconateCorrect answer
- DMethylene blue
- EFlumazenil
- FSodium bicarbonate
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