Toxicology USMLE Step 1 Practice Question
A 31-year-old man with opioid use disorder abruptly discontinues heroin. Two days later, he presents with piloerection, rhinorrhea, lacrimation, abdominal cramping, and yawning. Vital signs show BP 138/88 mmHg, HR 102 bpm, RR 18/min, and temperature 37.8°C. Physical examination reveals mydriasis and hyperreflexia. Urine drug screen is negative for opioids. He denies recent acetaminophen use. Which of the following best describes this syndrome?
Answer choices
- ALife threatening withdrawal usually causing seizures
- BSedative-hypnotic overdose
- CAnticholinergic intoxication
- DDigoxin toxicity
- EWithdrawal from opioidsCorrect answer
- FSympathomimetic intoxication from cocaine or amphetamine use
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