Toxicology USMLE Step 1 Practice Question
A 61-year-old man presents to the emergency department after intentional ingestion of sustained-release verapamil tablets. Vital signs show BP 78/52 mmHg, HR 38/min, RR 16/min, temperature 36.8°C, and SpO2 98% on room air. He is lethargic with a serum calcium of 8.2 mg/dL. Electrocardiography reveals severe bradycardia with prolonged PR interval. He denies chest pain. Which of the following therapies is most effective for managing severe calcium channel blocker toxicity?
Answer choices
- ADigoxin immune Fab
- BLeucovorin
- CPralidoxime
- DCalcium administrationCorrect answer
- EHydroxocobalamin
- FHigh-dose insulin euglycemic therapy
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