Thyroid Disorders USMLE Step 1 Practice Question
A 28-year-old woman at 8 weeks gestation presents for prenatal care. Her TSH is 6.2 mIU/L and free T4 is 0.9 ng/dL (low end of normal). She reports no symptoms. Thyroid peroxidase antibodies are positive. She has no prior thyroid disease. Which of the following is the most appropriate management?
Answer choices
- AMonitor TSH every 2 months without treatment
- BRefer for thyroid biopsy given antibody positivity
- CStart levothyroxine 50 mcg dailyCorrect answer
- DInitiate iodine supplementation only
- ERepeat TSH testing in one week; treat only if persistently elevated
- FStart propylthiouracil 50 mg three times daily
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