Thyroid Disorders USMLE Step 1 Practice Question
A 43-year-old woman presents with a 2-cm thyroid nodule discovered on palpation. She denies dysphagia, dyspnea, or neck pain. Vital signs: BP 128/82, HR 88, RR 16, Temp 37°C, SpO2 98%. Laboratory studies reveal suppressed TSH at 0.2 mIU/L (normal 0.4–4.0) with normal free T4. Thyroid ultrasound shows a solid, hypoechoic nodule without cystic features. She takes no thyroid medications. Which of the following is the best next step in evaluation?
Answer choices
- ARadioactive iodine uptake scanCorrect answer
- BMeasure anti-thyroid peroxidase antibodies
- CWater deprivation test
- DACTH stimulation test
- EImmediate total thyroidectomy
- FFine-needle aspiration biopsy of the nodule
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