Thyroid Disorders USMLE Step 1 Practice Question
A 26-year-old woman presents with a 3-month history of progressive weight loss despite increased appetite, palpitations, heat intolerance, and anxiety. Vital signs show BP 142/88 mmHg, HR 108 bpm, RR 18, temperature 37.8°C, and SpO2 98% on room air. Physical examination reveals a diffuse goiter, warm moist skin, and bilateral exophthalmos. TSH is suppressed at 0.08 mIU/L. Thyroid peroxidase antibodies are negative. Which diagnosis best explains these findings?
Answer choices
- AGraves diseaseCorrect answer
- BSubacute granulomatous thyroiditis
- CToxic adenoma
- DPituitary TSH adenoma
- EHashimoto thyroiditis
- FThyroid hormone factitia (thyroiditis from exogenous thyroid hormone ingestion)
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