Seizure Disorders USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Neurology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · hard1. A 16-year-old boy with a 3-year history of juvenile myoclonic epilepsy, currently controlled on monotherapy with valproic acid, presents to the emergency department after experi…
- USMLE Step 1 · easy2. A 68-year-old man presents with his first focal motor seizure involving the left leg followed by 48-hour post-ictal paralysis. Vitals: BP 142/88, HR 92, RR 18, Temp 37.2°C, SpO2…
- USMLE Step 1 · medium3. A 19-year-old woman presents to her neurologist 6 weeks after starting valproic acid for newly diagnosed idiopathic generalized epilepsy. She reports tremor, progressive weight…
- USMLE Step 1 · medium4. A 32-year-old woman with generalized tonic-clonic seizures controlled on lamotrigine for 3 years presents planning pregnancy. Vital signs are normal (BP 118/76, HR 72, RR 16, Te…
- USMLE Step 1 · medium5. A 7-year-old girl is brought to the emergency department after experiencing a focal seizure consisting of rhythmic jerking of her right arm and right corner of her mouth lasting…
- USMLE Step 1 · medium6. A 45-year-old man with a 10-year history of left temporal lobe epilepsy presents to clinic after experiencing 3 breakthrough seizures over the past month despite reported adhere…
- USMLE Step 1 · medium7. A 3-year-old boy presents with recurrent brief episodes of sudden loss of muscle tone lasting 5-10 seconds during play, after which he awakens alert. His mother reports he has h…
- USMLE Step 1 · medium8. A 24-year-old woman with no prior medical history presents to the emergency department after experiencing a generalized tonic-clonic seizure lasting 2 minutes. She reports irreg…
- USMLE Step 1 · hard9. A 72-year-old man with a 10-year history of hypertension presents to the emergency department with a generalized tonic-clonic seizure. His wife reports he suffered an acute isch…
- USMLE Step 1 · medium10. A 55-year-old man with newly diagnosed small-cell lung cancer presents with a single generalized tonic-clonic seizure. MRI brain reveals three hypodense lesions in the left temp…
- USMLE Step 1 · easy11. A 9-month-old infant presents with sudden onset of brief flexion of the trunk and extremities occurring in clusters, followed by crying. Episodes last 1-2 seconds and occur 10-1…
- USMLE Step 1 · hard12. A 38-year-old woman with a 5-year history of temporal lobe epilepsy presents to neurology clinic with recurrent breakthrough seizures over the past 3 months. She reports that du…
- USMLE Step 1 · medium13. A 7-year-old boy is brought to the emergency department after his first seizure. His parents report he was playing video games when he suddenly stopped responding, his body stif…
- USMLE Step 1 · medium14. A 62-year-old woman with a 10-year history of hypertension presents to the emergency department following a seizure episode. She reports that while sitting at dinner, she experi…
- USMLE Step 1 · easy15. A 3-year-old boy presents with multiple daily episodes of sudden staring and unresponsiveness lasting 5-10 seconds, occurring 10-20 times per day. Vital signs are normal: BP 95/…
- USMLE Step 1 · medium16. A 24-year-old woman presents to the emergency department after her first witnessed generalized tonic-clonic seizure. She reports a 2-year history of brief jerking movements of h…
- USMLE Step 1 · medium17. A 58-year-old man with history of left MCA stroke 8 years ago presents with sudden-onset focal motor seizure of the right arm, followed by Todd's paralysis lasting 36 hours. Vit…
- USMLE Step 1 · medium18. A 42-year-old woman with a 3-year history of focal onset seizures with impaired awareness presents for follow-up evaluation. She reports 2-3 breakthrough seizures per month desp…
- USMLE Step 1 · easy19. A 6-month-old infant presents with clusters of sudden brief flexion movements of the arms and trunk occurring 10-20 times per episode, dozens of episodes daily. The mother repor…
- USMLE Step 1 · medium20. A 24-year-old woman with no prior seizure history presents after a single generalized tonic-clonic seizure following 3 days of poor sleep, intense stress from medical school exa…
- USMLE Step 1 · easy21. A 7-year-old boy is brought to clinic by his mother who reports brief episodes of unresponsiveness occurring 5-10 times daily over the past 3 weeks. During these episodes, lasti…
- USMLE Step 1 · hard22. A 34-year-old man with temporal lobe epilepsy controlled on levetiracetam for 3 years presents with a 2-week history of mood lability, irritability, anger outbursts, and suicida…
- USMLE Step 1 · medium23. A 16-year-old girl presents to the neurology clinic with a 6-month history of three unprovoked generalized tonic-clonic seizures. Vital signs are stable. Brain MRI is normal. EE…
- USMLE Step 1 · easy24. A 52-year-old man with no seizure history presents with sudden-onset focal motor seizure involving the right arm lasting 2 minutes, followed by Todd's paralysis of the right arm…