Pituitary Disorders USMLE Step 1 Practice Question
A 41-year-old woman with diabetes mellitus presents with progressive coarse facial features, hand enlargement, and excessive sweating. Her fasting glucose is 180 mg/dL despite high-dose metformin. GH at 2.2 ng/mL after 75-g oral glucose tolerance test is markedly elevated. Which of the following is the most appropriate next diagnostic step?
Answer choices
- AStart octreotide therapy
- BMeasure IGF-1 levelCorrect answer
- COrder abdominal ultrasound
- DPerform 24-hour urinary free cortisol
- EAdminister metyrapone test
- FPerform high-dose dexamethasone suppression test
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