Organ System Pathology USMLE Step 1 Practice Question
A 41-year-old aerospace engineer presents with several months of progressive dyspnea, fatigue, and nonproductive cough. Vital signs show BP 128/82 mmHg, HR 92/min, RR 18/min, temperature 37.2°C, and SpO2 92% on room air. Chest CT reveals diffuse interstitial infiltrates and hilar lymphadenopathy. Serum calcium is elevated at 11.2 mg/dL. Lung biopsy demonstrates noncaseating granulomas. He denies fever or night sweats. Which of the following is the most likely diagnosis?
Answer choices
- AIdiopathic pulmonary fibrosis
- BSarcoidosis
- CBerylliosisCorrect answer
- DHypersensitivity pneumonitis
- ETuberculosis
- FChronic silicosis
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