Organ System Pathology USMLE Step 1 Practice Question
A 7-year-old girl presents with dark urine and facial puffiness two weeks after impetigo on her legs. Vital signs show BP 128/82 mmHg, HR 88 bpm, RR 20/min, temperature 37.2°C, and SpO2 98% on room air. Serum creatinine is 1.1 mg/dL, and complement C3 level is low. Urinalysis reveals hematuria and proteinuria. She denies recent upper respiratory infection. Which of the following is the most likely diagnosis?
Answer choices
- AMembranous nephropathy
- BMinimal change disease
- CFocal segmental glomerulosclerosis
- DPoststreptococcal glomerulonephritisCorrect answer
- EIgA nephropathy
- FLupus nephritis
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.