Organ System Pathology USMLE Step 1 Practice Question
A premature newborn (32 weeks gestation) presents with tachypnea (RR 68/min), poor weight gain, and feeding intolerance. Vital signs show BP 55/35 mmHg, HR 165/min, SpO2 98% on room air, and normal temperature. Cardiac examination reveals a continuous "machine-like" murmur at the left infraclavicular region. Chest X-ray demonstrates pulmonary edema and cardiomegaly. No hepatomegaly is noted on examination. Which medication would most likely promote closure of the patent ductus arteriosus?
Answer choices
- AMilrinone
- BProstaglandin E1 infusion
- CFurosemide
- DIndomethacinCorrect answer
- EDobutamine
- FSildenafil
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