Organ System Pathology USMLE Step 1 Practice Question
A 42 year old woman presents with progressive exertional dyspnea and intermittent hemoptysis. She emigrated from an area where streptococcal infections were common and reports repeated sore throats as a child. Examination shows an opening snap followed by a low pitched diastolic rumble best heard at the apex in the left lateral decubitus position. Which of the following is the most likely underlying etiology?
Answer choices
- ADystrophic calcification of a bicuspid valve
- BPost streptococcal autoimmune valvular scarringCorrect answer
- CAcute papillary muscle ischemia
- DMyxomatous degeneration of valve leaflets
- ECongenital failure of ductus arteriosus closure
- FDegenerative calcification of the mitral annulus
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