Organ System Pathology USMLE Step 1 Practice Question
A 9-year-old boy presents with a 6-month history of poor linear growth, progressive headaches, and declining school performance. Vital signs show BP 108/72 mmHg, HR 88 bpm, RR 18, temperature 37.2°C, SpO2 98% on room air. Physical examination reveals short stature and bitemporal hemianopsia. Brain MRI demonstrates a calcified suprasellar cystic mass. Morning fasting growth hormone level is 0.8 ng/mL. There is no precocious puberty. Which diagnosis best explains these findings?
Answer choices
- ACraniopharyngiomaCorrect answer
- BPilocytic astrocytoma
- CPituitary prolactinoma
- DMeningioma
- EMedulloblastoma
- FRathke cleft cyst without calcification or solid component
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