Organ System Pathology USMLE Step 1 Practice Question
A 49-year-old man with chronic alcohol use disorder presents for routine evaluation. Vital signs show BP 128/82 mmHg, HR 88/min, RR 16/min, temperature 37.2°C. Physical examination reveals mild hepatomegaly without ascites or jaundice. Laboratory studies show AST 72 U/L and ALT 45 U/L. Liver biopsy demonstrates large clear cytoplasmic vacuoles displacing hepatocyte nuclei peripherally. Which of the following terms best describes this histologic finding?
Answer choices
- ACholestasis
- BAmyloidosis
- CHydropic change
- DCoagulative necrosis
- ESteatosisCorrect answer
- FMallory-Denk intracytoplasmic eosinophilic inclusion bodies
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