Neuromuscular Disorders USMLE Step 1 Practice Question
A 19-year-old man develops muscle rigidity and high fever shortly after induction of general anesthesia with sevoflurane and succinylcholine. Vital signs show temperature 39.2°C, heart rate 142/min, blood pressure 158/92 mmHg, respiratory rate 28/min, and SpO2 92% on supplemental oxygen. Arterial blood gas reveals pH 7.25 with PaCO2 58 mmHg. Serum creatinine kinase is markedly elevated at 8,500 U/L. Urine myoglobin is positive. Recent medication history is unremarkable. Which of the following is the most appropriate treatment?
Answer choices
- APralidoxime
- BDantroleneCorrect answer
- CAtropine
- DNaloxone
- EMethylene blue
- FCalcium chloride
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