Neuromuscular Disorders USMLE Step 1 Practice Question
A 29-year-old male farm worker is brought to the emergency department 30 minutes after acute pesticide exposure. He presents with diaphoresis, excessive salivation, abdominal cramping, wheezing, and visible muscle fasciculations. Vital signs show BP 98/62, HR 118, RR 22, SpO2 89%. Serum cholinesterase activity is markedly decreased at 15% of normal. Pupils are pinpoint. He denies recent medication use. Which of the following is the most appropriate immediate antidotal therapy?
Answer choices
- AAtropine and pralidoximeCorrect answer
- BDantrolene and bromocriptine
- CEdrophonium and naloxone
- DPhysostigmine and atropine
- EPyridostigmine and glucagon
- FNeostigmine and epinephrine
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