Neurodegenerative Diseases USMLE Step 1 Practice Questions
64 board-style USMLE Step 1 questions in Neurology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 · medium25. A 58 year old woman reports a 5 year history of tremor that occurs when she writes checks and holds a coffee cup. The tremor improves after a small amount of wine. Her father ha…
- USMLE Step 1 · medium26. A 42 year old man is evaluated for involuntary movements and personality change. His father died in his early 50s after progressive dementia. Examination shows choreiform moveme…
- USMLE Step 1 · easy27. A 69 year old man is brought by his wife because of progressive slowing of movement and a tremor in his right hand at rest. He has difficulty initiating gait and his handwriting…
- USMLE Step 1 · medium28. A 63 year old man with a 50 pack year smoking history presents with progressive difficulty rising from a chair. He reports dry mouth and erectile dysfunction. Examination shows…
- USMLE Step 1 · medium29. A 34-year-old woman presents with progressive bilateral ptosis and diplopia that worsen in the evening. She reports difficulty chewing after prolonged meals and denies sensory c…
- USMLE Step 1 · easy30. A 24 year old man comes to the emergency department because of progressive weakness for 3 days. One week ago he had watery diarrhea after eating undercooked poultry. He now has…
- USMLE Step 1 · easy31. A 31 year old woman presents with blurry vision in her right eye and pain with eye movement for 2 days. Six months ago she had transient numbness of the left leg that resolved s…
- USMLE Step 1 · medium32. A 29 year old woman has progressive numbness over both shoulders and upper arms. She reports burning herself while cooking without noticing until later. Examination shows bilate…
- USMLE Step 1 · medium33. A 64 year old man presents with progressive gait instability and numbness in both feet. He underwent total gastrectomy 3 years ago for gastric cancer. Examination shows decrease…
- USMLE Step 1 · hard34. A 33 year old woman is admitted after a severe motor vehicle collision with flexion injury to the thoracic spine. Neurologic examination shows bilateral flaccid paralysis below…
- USMLE Step 1 · medium35. A 74 year old man with cervical spondylosis falls and strikes his chin on a countertop. He immediately develops weakness in both upper extremities that is worse than in his legs…
- USMLE Step 1 · medium36. A 27 year old man is stabbed in the right side of the back during an assault. After stabilization, neurologic examination shows spastic weakness and loss of vibration and positi…
- USMLE Step 1 · hard37. A 54-year-old man presents with cyanosis and dyspnea 4 hours after dental work with topical anesthesia. Vitals show HR 98 bpm, BP 132/78 mmHg, RR 22/min, SpO2 85% on room air. A…
- USMLE Step 1 · medium38. A 71-year-old man with Parkinson disease presents with tremor at rest and bradykinesia. Vital signs show BP 138/82 mmHg, HR 68 bpm, RR 16, temp 37.2°C. He is started on combinat…
- USMLE Step 1 · easy39. A 66-year-old woman presents with sudden severe right eye pain, headache, nausea, and vision of halos around lights. Vital signs show BP 158/92 mmHg, HR 102/min, RR 18/min, and…
- USMLE Step 1 · medium40. A 45-year-old woman presents with a 2-year history of progressive right-sided sensorineural hearing loss and tinnitus. She reports imbalance but denies vertigo. Vital signs: BP…
- USMLE Step 1 · medium41. A 48-year-old man presents with recurrent episodes of vertigo lasting 4-6 hours accompanied by left-sided tinnitus and progressive sensorineural hearing loss. Vital signs show B…
- USMLE Step 1 · medium42. A 46-year-old man presents with a 2-week history of right-sided neck pain following a motor vehicle accident. Vital signs show BP 138/82, HR 82, RR 16, and normal temperature. E…
- USMLE Step 1 · medium43. A 55-year-old woman with hypertension presents with sudden severe headache and diplopia. Vital signs show BP 168/98 mmHg, HR 88/min, RR 16/min, temp 37.2°C. Examination reveals…
- USMLE Step 1 · medium44. A 27-year-old woman presents with acute left gaze palsy; the right eye fails to adduct while the left eye demonstrates nystagmus. She reports transient monocular vision loss thr…
- USMLE Step 1 · medium45. A 58-year-old man presents with 6-month progressive hand weakness and muscle atrophy. Examination reveals visible fasciculations in bilateral upper extremities, brisk patellar r…
- USMLE Step 1 · medium46. A 32-year-old man presents with difficulty releasing his grip after a firm handshake. He reports frontal hair loss since his 20s, bilateral cataracts noted on ophthalmology exam…
- USMLE Step 1 · medium47. A 17-year-old boy presents with slowly progressive proximal muscle weakness and bilateral calf hypertrophy over 5 years. Vital signs: BP 118/76, HR 88, RR 16, Temp 37°C, SpO2 98…
- USMLE Step 1 · easy48. A 4-year-old boy presents with delayed motor milestones, frequent falls, and progressive difficulty rising from the floor. Vital signs: BP 95/60, HR 98, RR 20, Temp 37°C, SpO2 9…