Neurodegenerative Diseases USMLE Step 1 Practice Question
A 17 year old boy is evaluated for frequent ankle sprains and difficulty running. Examination shows high arches, hammer toes, distal lower extremity weakness, decreased vibration sense in the feet, and absent ankle reflexes. Nerve conduction studies show uniformly slow conduction velocities. Which of the following is the most likely diagnosis?
Answer choices
- AMyasthenia gravis
- BAmyotrophic lateral sclerosis
- CCharcot Marie Tooth diseaseCorrect answer
- DFriedreich ataxia
- ETabes dorsalis
- FHereditary neuropathy with liability to pressure palsies (HNPP)
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