Neurodegenerative Diseases USMLE Step 1 Practice Question
A 52 year old man with severe alcohol use disorder is brought to the emergency department because of confusion and unsteady gait. Examination shows horizontal nystagmus and bilateral lateral rectus weakness. He is given intravenous dextrose before vitamin supplementation and becomes more disoriented. Deficiency of which cofactor most likely underlies this syndrome?
Answer choices
- ABiotin
- BFolate
- CPyridoxine
- DThiamineCorrect answer
- ENiacin
- FCobalamin (vitamin B12)
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