Neurodegenerative Diseases USMLE Step 1 Practice Question
A 74-year-old man presents with progressive gait difficulty over one year. His wife reports urinary incontinence and cognitive decline. Vital signs: BP 152/88, HR 78, RR 16, temp 37°C, SpO2 98%. Examination reveals broad-based gait with magnetic quality and no focal neurologic deficits. Cognitive screening shows mild memory impairment. MRI demonstrates ventriculomegaly with normal ventricular-to-brain ratio and minimal cortical atrophy. CSF opening pressure is normal. Which diagnosis best explains this clinical triad?
Answer choices
- AFrontotemporal dementia
- BVascular dementia
- CAlzheimer disease
- DNormal pressure hydrocephalusCorrect answer
- EParkinson disease
- FSubdural hematoma
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