Neurodegenerative Diseases USMLE Step 1 Practice Question
A 58-year-old man presents with progressive headaches, personality changes, and new-onset seizures over 3 months. Vital signs: BP 148/92 mmHg, HR 94 bpm, RR 18, Temp 37.2°C, SpO2 98% on room air. MRI shows a heterogeneously enhancing mass crossing the corpus callosum with surrounding vasogenic edema. Serum glucose and electrolytes are normal. He denies recent head trauma or focal neurologic deficits. Which of the following is the most likely diagnosis?
Answer choices
- AOligodendroglioma
- BPilocytic astrocytoma
- CMeningioma
- DSchwannoma
- EGlioblastomaCorrect answer
- FPrimary CNS lymphoma
See the full explanation
Get the correct-answer rationale, why each distractor is wrong, the underlying mechanism, and high-yield associations — plus adaptive practice that targets your weak areas — with a free MedBoardPRO account.