Neurodegenerative Diseases USMLE Step 1 Practice Question
A 43-year-old man presents with a 2-year history of progressive involuntary choreiform movements, irritability, and cognitive decline affecting work performance. Vital signs: BP 128/82, HR 92, RR 16, Temp 37°C, SpO2 98%. His father died of similar symptoms at age 50. Brain MRI shows bilateral caudate atrophy. The patient denies substance use and reports no recent head trauma. Which of the following is the most likely diagnosis?
Answer choices
- AHuntington diseaseCorrect answer
- BWilson disease
- CEssential tremor
- DParkinson disease
- EMyasthenia gravis
- FSydenham chorea
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