Metabolism USMLE Step 1 Practice Question
A 34 year old man is brought to the emergency department 8 hours after ingesting windshield washer fluid during a suicide attempt. He complains of blurry vision and abdominal pain. Laboratory studies show an anion gap metabolic acidosis. He is treated with fomepizole. Which of the following changes in the alcohol dehydrogenase reaction is most likely produced by this medication?
Answer choices
- AIncreased Km with unchanged VmaxCorrect answer
- BDecreased Km with unchanged Vmax
- CDecreased Km with decreased Vmax
- DUnchanged Km with decreased Vmax
- EIncreased Vmax with unchanged Km
- FUnchanged Km with unchanged Vmax
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