Metabolism USMLE Step 1 Practice Question
A 34-year-old male with newly diagnosed hyperlipidemia presents with fatigue and recurrent infections. Vital signs: BP 128/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. Laboratory studies show elevated triglycerides (320 mg/dL) and decreased hepatic NADPH/NADP+ ratio. Liver ultrasound is unremarkable. He denies alcohol use. Which metabolic pathway would be most stimulated to restore the hepatic NADPH/NADP+ balance needed for lipogenesis and antioxidant defense?
Answer choices
- AA
- BE
- CC
- DBCorrect answer
- ED
- FF
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