Metabolism USMLE Step 1 Practice Question
A 34-year-old man with type 2 diabetes presents with fatigue and dyspnea on exertion. Vital signs show BP 142/88 mmHg, HR 98 bpm, RR 20/min, temp 37.2°C, SpO2 98% on room air. Serum glucose is 284 mg/dL; creatine kinase is elevated at 450 U/L. He denies chest pain. During aerobic metabolism, succinate thiokinase catalyzes succinyl-CoA cleavage, generating a high-energy compound. This compound subsequently participates in which of the following biochemical pathways?
Answer choices
- AIsopentyl pyrophosphate synthesis
- BOxidative phosphorylation
- CEpinephrine synthesis from tyrosineCorrect answer
- DCysteine degradation
- EElongation of the polypeptide chain
- FFatty acid synthesis using malonyl-CoA as the activated carbon donor
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