Histology USMLE Step 1 Practice Question
A 34-year-old woman presents with a 3-month history of progressive polyarticular joint pain and morning stiffness lasting more than 2 hours. Physical examination reveals symmetric swelling of the hands and wrists. Laboratory studies show ESR 52 mm/hr, CRP 8.2 mg/dL, and negative rheumatoid factor. A synovial biopsy from the wrist is obtained and shows hyperplastic synovial lining with increased macrophages and lymphocytic infiltrate in the sublining layer. Which of the following best describes the thickness of the normal synovial intimal lining layer?
Answer choices
- A1-2 cell layersCorrect answer
- B3-5 cell layers
- C8-10 cell layers
- D15-20 cell layers
- E25-30 cell layers
- F50-75 cell layers
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