Hepatobiliary Disease USMLE Step 1 Practice Question
A 45-year-old woman with a 15-year history of primary biliary cholangitis presents with progressive fatigue, pruritus, and jaundice. Laboratory studies show elevated alkaline phosphatase and direct bilirubin, with positive antimitochondrial antibodies. She reports recent onset xanthomas on her elbows. Which of the following is the most appropriate initial pharmacologic management?
Answer choices
- AAzathioprine
- BCorticosteroids
- CUrsodeoxycholic acidCorrect answer
- DPenicillamine
- EInterferon-alpha
- FMethotrexate
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