Hepatobiliary Disease USMLE Step 1 Practice Question
A 62-year-old woman presents with fever, jaundice, and right upper quadrant pain. Vital signs show BP 105/68 mmHg, HR 102 bpm, RR 20/min, temperature 38.9°C, and SpO2 98% on room air. Laboratory studies reveal elevated alkaline phosphatase (245 U/L), direct bilirubin (4.2 mg/dL), and WBC 13,200/μL. Abdominal ultrasound demonstrates dilated intrahepatic bile ducts. She denies pruritus. Which of the following is the most likely diagnosis?
Answer choices
- AAcute ascending cholangitisCorrect answer
- BAcute appendicitis
- CPrimary biliary cholangitis
- DAcute hepatitis A infection
- EGilbert syndrome
- FAcute pancreatitis with secondary bile duct obstruction
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