Glomerular Diseases USMLE Step 1 Practice Question
Two weeks after undergoing an emergency cardiac catheterization for unstable angina pectoris, a 65-year-old man has decreased urinary output. He takes naproxen for osteoarthritis and was started on aspirin, clopidogrel, and metoprolol after the coronary intervention. His temperature is 38.1°C (100.5°F), pulse is 96/min, and blood pressure is 128/88 mm Hg. Examination shows mottled, reticulated purplish discoloration of the feet and ischemic changes on the right big toe. His leukocyte count is 16,500/mm3 with 56% segmented neutrophils, 12% eosinophils, 30% lymphocytes, and 2% monocytes. His serum creatinine concentration is 4.5 mg/dL. A photomicrograph of a kidney biopsy specimen is shown. Which of the following is the most likely cause of this patient's presentation?
Answer choices
- AAllergic interstitial nephritis
- BCholesterol embolizationCorrect answer
- CContrast-induced nephropathy
- DRenal papillary necrosis
- EEosinophilic granulomatosis with polyangiitis
- FThrombotic thrombocytopenic purpura
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