Glomerular Diseases USMLE Step 1 Practice Question
A 26-year-old man with no significant past medical history presents with acute kidney injury, hematuria with dysmorphic RBCs and RBC casts, and mild hypertension. He denies recent URI. Renal biopsy shows crescents in >50% of glomeruli with fibrinoid necrosis. ANCA and anti-GBM antibodies are both negative. Which of the following is the most likely diagnosis?
Answer choices
- AAnti-GBM disease
- BLupus nephritis Class IV
- CANCA-associated vasculitis
- DANCA-negative pauci-immune crescentic GNCorrect answer
- EPost-infectious glomerulonephritis
- FImmune complex membranoproliferative glomerulonephritis
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