Glomerular Diseases USMLE Step 1 Practice Question
A 32-year-old woman presents 2 weeks after pharyngitis with gross hematuria, periorbital edema, and hypertension (BP 148/92 mmHg, HR 88, RR 16, Temp 37.2°C, SpO2 98%). Urinalysis reveals RBC casts and 2+ proteinuria. Serum creatinine is 1.3 mg/dL (baseline 0.8). Complement C3 level is 45 mg/dL (normal 90-180). C4 and ASO titer are normal. She denies arthralgias. Which of the following is the most likely diagnosis?
Answer choices
- ASystemic lupus erythematosus
- BPost-streptococcal glomerulonephritisCorrect answer
- CANCA-associated vasculitis
- DIgA nephropathy
- EHereditary nephritis
- FMembranoproliferative glomerulonephritis associated with hepatitis C
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