Glomerular Diseases USMLE Step 1 Practice Question
A 43-year-old woman presents with progressive generalized edema and weight gain. Vital signs show BP 138/88 mmHg, HR 88 bpm, RR 16, temperature 37°C, SpO2 98% on room air. Urinalysis reveals 4+ proteinuria without hematuria or casts. Laboratory studies show serum albumin 1.9 g/dL, total cholesterol 380 mg/dL, and serum creatinine 0.9 mg/dL. She denies recent infections or medication use. Which renal syndrome best explains these clinical and laboratory findings?
Answer choices
- ANephritic syndrome with active urinary sediment
- BRenal tubular acidosis
- CAcute tubular necrosis
- DPrerenal azotemia
- ENephrotic syndrome with heavy protein lossCorrect answer
- FChronic glomerulonephritis with progressive renal insufficiency
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