Glomerular Diseases USMLE Step 1 Practice Question
A 44-year-old man with chronic hepatitis B infection presents with progressive bilateral lower extremity edema and frothy urine for 3 weeks. Vital signs: BP 148/92 mmHg, HR 88/min, RR 16/min, Temp 37°C, SpO2 98% on room air. Serum albumin is 2.1 g/dL. Urinalysis shows 3+ proteinuria without hematuria. Nephrotic-range proteinuria is confirmed on 24-hour urine collection. Which glomerular disease is most likely responsible?
Answer choices
- AMembranous nephropathyCorrect answer
- BAnti-GBM disease
- CAlport syndrome
- DMinimal change disease
- EAcute postinfectious glomerulonephritis
- FMembranoproliferative GN (HCV-associated)
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