Glomerular Diseases USMLE Step 1 Practice Question
A 14-year-old boy presents with persistent hematuria and progressive high-frequency sensorineural hearing loss. Ophthalmologic examination reveals anterior lenticonus. Vital signs show BP 128/82 mmHg, HR 88 bpm, RR 16, temp 37°C, SpO2 98% on room air. Serum creatinine is 1.1 mg/dL. Urinalysis demonstrates dysmorphic red blood cells and red blood cell casts; proteinuria is absent. He denies recent URI or skin infection. Which diagnosis best explains this clinical triad?
Answer choices
- AAlport syndromeCorrect answer
- BIgA nephropathy
- CThin basement membrane disease
- DMembranous nephropathy
- EMinimal change disease
- FHereditary nephritis with normal hearing and vision
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