General Pathology USMLE Step 1 Practice Question
A 58-year-old woman presents with a palpable left breast mass. Vital signs show BP 128/82, HR 82, RR 16, temp 37°C, SpO2 98%. Mammography reveals a 2.3 cm irregular density with microcalcifications. Biopsy confirms invasive ductal carcinoma. Sentinel lymph node biopsy demonstrates metastatic disease within axillary nodes. Chest CT shows no distant metastases. She denies systemic symptoms. This pattern of initial lymph node spread is most characteristic of which tumor type in general?
Answer choices
- ALeukemias spreading by direct implantation
- BCarcinomas spreading through lymphaticsCorrect answer
- CSarcomas spreading hematogenously
- DMelanomas confined to the epidermis
- EGliomas seeding through cerebrospinal fluid only
- FLymphomas spreading through contiguous lymph node involvement
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