General Pathology USMLE Step 1 Practice Question
A 42-year-old woman undergoes appendectomy for acute appendicitis. Her postoperative course is complicated by wound erythema and edema on postoperative day 5. Vital signs show HR 88 bpm, BP 128/76 mmHg, temp 37.2°C. The incision site appears pink and soft without purulent drainage. Wound culture remains negative. Microscopy demonstrates proliferating capillaries, fibroblasts, and loose extracellular matrix with minimal collagen deposition. Which tissue type best describes these histologic findings?
Answer choices
- ADysplastic epithelium with loss of maturation
- BGranulation tissue rich in type III collagen and new blood vesselsCorrect answer
- CCaseous necrosis with acellular cheese like debris
- DKeloid tissue with disorganized type I collagen extending beyond the wound margins
- EFibrinoid necrosis due to plasma protein leakage into vessel walls
- FMature fibrous scar with dense type I collagen and few cells
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