General Pathology USMLE Step 1 Practice Question
A 38 year old man employed in an industrial cleaning facility is accidentally exposed to carbon tetrachloride. Several hours later he develops right upper quadrant pain and elevated aminotransferases. Toxic metabolism generates free radicals that initiate lipid peroxidation of cellular membranes. Which organelle is most directly involved in the formation of this toxic metabolite?
Answer choices
- AGolgi apparatus
- BSmooth endoplasmic reticulumCorrect answer
- CRough endoplasmic reticulum
- DLysosome
- ENucleolus
- FMitochondrial matrix
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