General Pathology USMLE Step 1 Practice Question
A 67 year old man comes to the emergency department with 90 minutes of crushing substernal chest pain radiating to the left arm. He has hypertension, hyperlipidemia, and a 40 pack year smoking history. ECG shows ST segment elevations in leads V1 to V4. Troponin I is elevated. He undergoes urgent reperfusion but dies 2 days later from cardiogenic shock. Histologic examination of the affected myocardium would most likely show which of the following patterns of tissue injury?
Answer choices
- ASaponification with chalky white calcium deposits in fat
- BEnzymatic digestion with loss of tissue architecture and pus formation
- CGranular amorphous debris surrounded by epithelioid histiocytes
- DPreserved tissue architecture with intensely eosinophilic anucleate cellsCorrect answer
- EImmune complex deposition in vessel walls with bright pink fibrin like material
- FDystrophic calcification with basophilic calcium deposits within the necrotic myocardium
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