Fungal and Parasitic Infections USMLE Step 1 Practice Question
A 42-year-old woman from Ohio presents to dermatology with a 6-month history of a slowly enlarging, painless nodular lesion on her forearm. She reports frequent exposure to soil while gardening. Physical examination reveals a firm, indurated nodule with minimal surrounding erythema. Vital signs are stable with no fever. Chest X-ray is normal without hilar lymphadenopathy or pulmonary infiltrates. Histopathology of a skin biopsy demonstrates granulomatous inflammation with broad-based budding yeast forms. Which of the following organisms is most likely responsible for this patient's skin lesion?
Answer choices
- ABlastomyces dermatitidisCorrect answer
- BSporothrix schenckii
- CHistoplasma capsulatum
- DCryptococcus neoformans
- ECoccidioides immitis
- FParacoccidioides brasiliensis
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