Fungal and Parasitic Infections USMLE Step 1 Practice Question
A 45-year-old woman with COPD presents with hemoptysis, fever (38.5°C), and productive cough for 3 weeks. Vital signs show HR 102/min, RR 22/min, SpO2 88% on room air. Chest X-ray reveals a cavitary lesion in the right lung apex with an air-fluid level. Sputum culture grows Aspergillus fumigatus. She has no dyspnea at rest and completed tuberculosis treatment 10 years ago. Which diagnosis best explains this presentation?
Answer choices
- AChronic granulomatous disease of the lung
- BAspergillus pneumonia with sepsis
- CAllergic bronchopulmonary aspergillosis
- DAcute invasive aspergillosis
- EAspergilloma (fungus ball)Correct answer
- FPulmonary tuberculosis with secondary mycobacterial infection
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