Endocrine Pharmacology USMLE Step 1 Practice Question
A 17-year-old boy with mild hemophilia A presents for elective dental extraction. His hematologist administers an intranasal medication to increase von Willebrand factor and factor VIII release from endothelial Weibel-Palade bodies prior to the procedure. Vital signs are stable (BP 118/76, HR 82, RR 16, Temp 37°C). Laboratory studies show baseline factor VIII activity at 35% and a prolonged partial thromboplastin time. Physical examination reveals no active bleeding or joint swelling. The patient denies headache or chest pain and takes no home medications. Which drug was most likely administered?
Answer choices
- AOctreotide
- BHydrocortisone
- COxytocin
- DTolvaptan
- EDesmopressinCorrect answer
- FVasopressin
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