Endocrine Pharmacology USMLE Step 1 Practice Question
A 62-year-old postmenopausal woman with osteoporosis presents with progressive lower back pain for three months. Vital signs: BP 128/76, HR 78, RR 16, Temp 37°C, SpO2 98%. Recent DEXA scan shows a T-score of -2.8 at the lumbar spine, and serum calcium is 9.4 mg/dL. Physical examination reveals mild thoracic kyphosis. She has a first-degree relative with breast cancer and denies vaginal bleeding. She seeks a medication that reduces vertebral fracture risk while lowering breast cancer risk without causing endometrial stimulation. Which of the following drugs best meets this goal?
Answer choices
- ARaloxifeneCorrect answer
- BCalcitonin
- CAlendronate
- DTeriparatide
- ETamoxifen
- FIbandronate
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