Endocrine Pharmacology USMLE Step 1 Practice Question
A 24-year-old woman with autoimmune primary adrenal insufficiency treated with hydrocortisone monotherapy presents with orthostatic dizziness and salt craving. Vital signs show BP 98/62 mmHg, HR 102 bpm, RR 18/min. Laboratory studies reveal serum potassium 5.8 mEq/L, sodium 128 mEq/L, and elevated plasma renin activity. Thyroid function tests are normal. She denies polyuria. Which medication should be added to address her mineralocorticoid deficiency?
Answer choices
- AHydrocortisone
- BSpironolactone
- CFludrocortisoneCorrect answer
- DEplerenone
- EDesmopressin
- FLicorice root supplement
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