Endocrine Pharmacology USMLE Step 1 Practice Question
A 31-year-old woman with Graves disease started antithyroid therapy 6 weeks ago. She now presents with fever (38.9°C), severe pharyngitis, and malaise. Vital signs show tachycardia (110 bpm) and tachypnea (20 breaths/min). Laboratory studies reveal WBC 1,200/μL with marked neutropenia; TSH and free T4 are appropriately suppressed. Pregnancy test is negative. She denies recent infections or other medications. Which antithyroid drug most likely caused this adverse effect?
Answer choices
- ARadioactive iodine
- BDesmopressin
- CMethimazoleCorrect answer
- DLevothyroxine
- EPropranolol
- FPotassium perchlorate
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