Endocrine Pharmacology USMLE Step 1 Practice Question
A 35-year-old woman with Hashimoto thyroiditis started levothyroxine replacement 3 months ago but continues experiencing fatigue and constipation. Vital signs: BP 128/82, HR 58, RR 14, Temp 36.8°C. TSH remains elevated at 8.2 mIU/L despite compliance. She takes her morning medication simultaneously with prenatal vitamins and calcium carbonate. Physical examination reveals no signs of hyperthyroidism. Which of the following best explains her persistent hypothyroid symptoms?
Answer choices
- ALiothyronine
- BPotassium iodide
- CPropylthiouracil
- DLevothyroxineCorrect answer
- EMethimazole
- FDesiccated thyroid extract
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