Endocrine Pharmacology USMLE Step 1 Practice Question
A 60-year-old man with type 2 diabetes mellitus presents with a fasting glucose of 110 mg/dL but postprandial glucose of 280 mg/dL due to irregular meal timing throughout the day. Vital signs are stable: BP 138/82, HR 78, RR 16, temp 37°C. HbA1c is 7.8%. Physical exam reveals mild central obesity with a BMI of 29 kg/m². He denies hypoglycemic episodes and takes metformin 1000 mg twice daily. His physician prescribes a short-acting insulin secretagogue taken immediately before meals to reduce postprandial glucose excursions. Which drug was most likely prescribed?
Answer choices
- AInsulin glargine
- BMetformin
- CGlyburide
- DRepaglinideCorrect answer
- EPioglitazone
- FNateglinide
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