Endocrine Pharmacology USMLE Step 1 Practice Question
A 55-year-old woman with type 2 diabetes mellitus presents with fatigue and polyuria. Vital signs: BP 138/82 mmHg, HR 88/min, RR 16/min, temperature 37°C, SpO2 98% on room air. Recent HbA1c is 8.2%. She denies chest pain or shortness of breath. Her physician prescribes an oral antidiabetic agent that increases endogenous insulin secretion by closing ATP-sensitive potassium channels in pancreatic beta cells. Which of the following drugs works by this mechanism?
Answer choices
- AMetformin
- BAcarbose
- CEmpagliflozin
- DPioglitazone
- EGlyburideCorrect answer
- FGlipizide
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