Endocrine Pharmacology USMLE Step 1 Practice Question
A 19-year-old man with type 1 diabetes mellitus presents to the emergency department with abdominal pain, vomiting, and confusion. He has not taken insulin in 48 hours. Vital signs show BP 102/58 mmHg, HR 118/min, RR 28/min, temperature 37.2°C. Laboratory studies reveal glucose 620 mg/dL, arterial pH 7.18, bicarbonate 10 mEq/L, anion gap 16 mEq/L, potassium 5.9 mEq/L, and positive serum ketones. Mucous membranes are dry and Kussmaul respirations are noted on examination. Which insulin preparation is most appropriate to initiate intravenously at this time?
Answer choices
- ARegular insulinCorrect answer
- BInsulin lispro
- CInsulin glargine
- DNPH insulin
- EInsulin degludec
- FInsulin detemir
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